En español
NIDA

Menu

National RX Drug Abuse Summit

April 21, 2014

Abuse of prescription opioids, stimulants, and other psychotherapeutic medications presents unique challenges. On the one hand, these drugs can produce serious harm (even death) when not taken as prescribed; on the other, they are powerful clinical allies that can be life saving.  Thus, the approach we take and the messages we convey to minimize harm need to be nuanced and multipronged.

RX Drug Abuse Summit logo

This week I have the opportunity to meet with a group of impassioned stakeholders who have gathered in Atlanta, GA for the third annual National Rx Drug Abuse Summit. The Summit brings together people on all sides of the problem, including representatives from government agencies, law enforcement, and the treatment world. This year it is an impressive roster: NIH director Francis Collins is also here, along with Michael Botticelli, acting director of the White House Office of the National Drug Control Policy, and Dr. Thomas R. Frieden, director of the CDC, as well as representatives from the FDA and SAMHSA. The Summit is organized by Operation UNITE, which was founded by Representative Hal Rogers, Chair of the House Appropriations Committee, who is also speaking.

This high level of interest reflects the urgency of the prescription drug abuse problem in the United States. Every day about 105 Americans die from drug overdose, and the majority of those deaths now involve prescription drugs—usually opioid painkillers. In 2012, 2.1 million Americans were addicted to prescription opioids. We are currently also seeing a rise in heroin use and its consequences as people who are addicted to painkillers graduate to those drugs’ cheaper street relative.

Many areas of NIDA research are contributing to reducing this problem, including our advancement of research into pain and efforts to advance pain education in medicine, our research to develop new treatments for opioid addiction, and research to develop new pain treatments including pain medications with less potential for abuse. For example, NIDA is partnering with a pharmaceutical company called Signature Therapeutics to develop an abuse deterrent formulation of the widely abused painkiller OxyContin. This formulation will use prodrug technology—attaching an extension to the opioid molecule that renders it neutral (unable to interact with opioid receptors) if injected, snorted, or smoked; instead it must pass through the digestive system to begin the process of releasing the opioid.

I recently wrote about naloxone and how increased access to this opioid antagonist could help save many people from dying of opioid overdoses. Currently, it is only approved in injectable formulations, but NIDA is supporting several projects to develop intranasal delivery systems. Earlier this month, the FDA approved a hand-held naloxone auto-injector device called Evzio, which can be used by family members or other caregivers and thus also increases its potential to save lives.  Naloxone has a  high safety profile and no abuse potential; thus, advances in delivery devices that can increase its availability and usability are likely to have a large impact on the opioid (and heroin) overdose epidemic.   

While complex, the problem of prescription drug abuse is by no means insurmountable. We are continuously learning more about these drugs’ effects in the brain, and we are converging on new prevention and treatment approaches that, I hope, will soon begin to reverse the alarming statistics. But solving the problem also requires working across agencies and across public and private structures, so it is gratifying to be here in Atlanta among so many policymakers, scientists, and community stakeholders who all share the same goal of reversing this public health epidemic.

This page was last updated April 2014

Comments

Re - National Rx Drug Abuse Summit article

As a recovering addict who spent almost 2 years in a methadone clinic after more than 10 years of opiate use, I honestly feel the only way to combat the Rx abuse problem is through prevention. A methadone or other maintenance program that is well managed and coupled with proper counseling can be life saving for those already addicted. However, they are expensive (treatment can cost more than using), and they are also few and far between. When I moved away from my clinic I was almost weaned off, had a job I loved, and was starting to see the light at the end of the tunnel. Now I can't afford to travel 100 miles every morning, therefore I'm afraid to even attempt to hold down a job. When I go without it is all I can do to handle my online classes. By the time you are eligible for these treatment facilities (addicted for at least a year) the road to recovery is long, hard, and virtually impossible. Stricter policies for prescribing doctors are needed, over the years I have met a LOT of pill addicts, and many of them were first exposed to opiates legally. Many people such as myself get addicted by self medicating for legitimate medical problems they simply can't afford to treat. We have to stop this addiction before it starts, period. Once addicted to opiates your life is over, and any and all potential you once had wasted. I would rather have cancer than this addiction, it has a higher survival rate. New drugs for withdrawal symptoms are desperately needed, but education is the only way to stop this. Not from people like you, it has to come from people like me. High school kids need to hear first hand how horrible life as an addict is. The common mentality of a teenager is that of "it can't happen to me." They need to know and understand that using opiates recreationally WILL turn into addiction. Physical dependency is not something you can "Just Say No" to. A day in the life of an addict should be as mandatory to a high school senior as writing a research paper. For those students already using and close to addiction, they should be able to receive help without fear of retribution.

Find Help Near You

The following website can help you find substance abuse or other mental health services in your area: www.samhsa.gov/Treatment. If you are in an emergency situation, people at this toll-free, 24-hour hotline can help you get through this difficult time: 1-800-273-TALK. Or click on: www.suicidepreventionlifeline.orgExternal link, please review our disclaimer.. We also have step by step guides on what to do to help yourself, a friend or a family member on our Treatment page.

Add new comment

Get this Publication

    About This Blog

    Welcome to my blog, here I highlight important work being done at NIDA and other news related to the science of drug abuse and addiction.

    Dr. Nora Volkow: Video Highlights

    NIDA Director, Dr. Nora D. Volkow Videos